Table 1.

The potential susceptibility loci identified in the ‘Immunochip’ study for Behcet’s disease

Number	SNP	Nearest gene(s)	Chromosome	Reported p values*
1	rs17753641†	IL12A	3	8.11E−10
2	rs17810546†	IL12A	3	1.01E−07
3	rs601338‡	FUT2	19	6.51E−09
4	rs1047781‡	FUT2	19	6.50E−04
5	rs3783550	IL1A–IL1B	2	1.29E−08
6	rs913678	CEBPB–PTPN1	20	1.10E−09
7	rs7075773§	ADO-EGR2	10	1.69E−09
8	rs1509966‡	ADO-EGR2	10	1.47E−06
9	rs224127‡	ADO-EGR2	10	1.56E−06
10	rs9316059‡	LACC1	13	1.16E−05
11	rs10176241	THADA	2	3.05E−05
12	rs79891766†	LONRF2	2	3.60E−05
13	rs116379815†	RBM6	3	4.17E−07
14	rs11248047	CPLX1	4	1.27E−07
15	rs13190001†	C5orf56	5	1.19E−05
16	rs17705333	INHBA	7	1.82E−05
17	rs9656588	IKZF1	7	5.28E−06
18	rs10094579	RIPK2	8	6.03E−07
19	rs2230801‡	RIPK2	8	9.60E−06
20	rs911603	TNFSF8	9	1.17E−05
21	rs28734985	IPMK-UBE2D1	10	4.10E−05
22	rs1698386§†	IPMK-UBE2D1	10	1.36E−05
23	rs10896027	MAP3K11-RELA	11	2.58E−05
24	rs58950470§	MAP3K11-RELA	11	6.25E−07
25	rs4906762	ATP10A	15	3.81E−05
26	rs3844576	SOCS1-TNP2	16	3.09E−06
27	rs1793978	CKM-KLC3	19	2.70E−05

*The association of SNPs reported by the Immunochip study in Turkish patients.

†Some SNPs (six in total) were excluded since they were not polymorphic in Han Chinese (rs17753641, rs17810546, rs79891766, rs116379815, rs13190001 and rs1698386). The SNPrs2647935, with p<5×10⁻⁵, was selected as an alternative SNP in IL12A.

‡The SNPs identified by meta-analysis.

§Imputed SNPs that with more significant association than the lead SNPs in loci and that is not in high linkage disequilibrium with lead SNPs in Chinese Han population (r² <0.8, Han Chinese Beijing).

SNP, single nucleotide polymorphism.