Skip to main content
. 2018 Jun 15;102(9):1308–1314. doi: 10.1136/bjophthalmol-2017-311753

Table 4.

Meta-analysis of multiple populations for the markers replicated in the Han Chinese cohorts

Marker (loci) Risk allele Population OR 95% CI P values I2 Phet values
rs913678 (CEBPB-PTPN1) C Turkish 1.33 1.21 to 1.46 1.10E−09 0 0.92
Iranian 1.29 1.13 to 1.48 1.59E−04
Han Chinese 1.30 1.15 to 1.46 1.37E−05
Meta-analysis 1.31 1.23 to 1.40 2.09E−-16
rs9316059 (LACC1) T Turkish 0.79 0.71 to 0.88 1.16E−05 0.45 0.16
Japanese 0.67 0.56 to 0.82 5.41E−05
Han Chinese 0.69 0.61 to 0.78 2.25E−09
Meta-analysis 0.73 0.68 to 0.79 2.96E−16
rs10094579 (RIPK2) A Turkish 1.34 1.19 to 1.50 6.03E−07 0 0.73
Han Chinese 1.30 1.15 to 1.47 3.15E−05
Meta-analysis 1.32 1.21 to 1.44 9.21E−-11
rs224127 (ADO-EGR2) A Turkish 1.26 1.15 to 1.39 1.56E−06 0 0.94
Japanese 1.30 1.11 to 1.51 1.10E−03
Han Chinese 1.27 1.14 to 1.42 1.71E05
Meta-analysis 1.27 1.19 to 1.36 5.28E−-13

Meta-analysis was performed for populations in which association for the variant exceeded the replication threshold.

I2, inconsistency index; phet, p for heterogeneity.