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. 2018 Jun 12;77(9):1345–1353. doi: 10.1136/annrheumdis-2017-212627

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Schematic figure showing the process of immune complex purification with following solubilisation and measurement of individual anti-citrullinated protein/peptide antibody reactivities. Details of the procedure are described in the Patients and methods section and online supplementary file. IC, immune complexes.