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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Rheumatology (Oxford). 2018 Apr 1;57(4):748–755. doi: 10.1093/rheumatology/kex447

Figure 4. Histological findings in paws with collagen-induced arthritis after one dose of treatment.

Figure 4

A, B. Right hindleg of a mouse 12h post treatment (score 0; initial score 2) with neutrophils only found in bone marrow, T - tibial bone; * joint space; C – cartilage. C. Left hindleg of a mouse 24h post treatment (score 0; initial score 2). D. Right foreleg of a mouse 72h post treatment (score 0; initial score 3), R - radial bone. B, C: Arrows: accumulations of viable and degenerate neutrophils. A, C (left), D: HE stain; B, C (right): staining for neutrophils (Ly6G+); ABC method, hemalaun counterstain. Bars = 2.5 mm (A, D) and 100 μm (B, C).