Fig 6. Summary of significantly enriched conserved MAU sites in ordered and disordered regions at 11 evolutionary clades.

Evolutionary levels with significant enrichment (after correction for multiple hypotheses) are labelled with four different shapes: lysine methylation (square), arginine methylation (circle), lysine acetylation (star) and ubiquitination (triangle) sites. The ordered and disordered regions with enriched MAU sites are labelled in olive green and peach respectively and the sites with significant enrichment in both disordered and ordered regions are coloured blue. Where there are conservation signals for newly emerged MAU sites in ordered and disordered regions the symbols are marked with black and red borders respectively. The results are depicted in more detail (with P-values, specific thresholds and total numbers of sites) in S1 File. Table A in S1 File is for the total data set, and Table B in S1 File is for histones.