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. 2018 Mar 6;25(4):353–360. doi: 10.1093/dnares/dsy007

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© The Author(s) 2018. Published by Oxford University Press on behalf of Kazusa DNA Research Institute.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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(A) Breakpoint junction sequence of the der(9) chromosome. Upper, middle and lower sequences indicate reference sequence of chromosome 14, derivative chromosome and reference sequence of chromosome 9, respectively. Breakpoint positions are marked with arrowheads. Numbers are based on the nucleotide position in the UCSC genome browser (GRCh37/hg19). Cen, centromere; tel, telomere. (B) The nucleotide and amino acid sequences of the fusion gene. The chimeric WASH1–NPAS3 gene shows in-frame fusion of exon 2 of WASH1 to exon 3 of NPAS3.