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Indel mutations introduced by CRISPR-mediated genome editing. (A) Schematic of CRISPR-mediated genome editing in Raji cells. (B) DNA sequences around the CRISPR target site in the THYN1 locus in WT and genome-edited cells. The forward DNA sequences of both alleles are shown. The CRISPR target sites in WT are underlined, and PAM positions are shown in red. An arrow indicates the CRISPR cleavage sites.
