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. 2018 May 29;25(4):421–437. doi: 10.1093/dnares/dsy014

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© The Author(s) 2018. Published by Oxford University Press on behalf of Kazusa DNA Research Institute.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Distribution of genes that produce splice isoform and AS event with different models. (a) The total number of loci according to isoforms of FLNC in PacBio Iso-deq data. (b) Annotated loci and isoforms were based on FLNC mapped to reference genome. (c) Five basic models of AS: exon skipping, intron retention, alternative donor site, alternative acceptor site and mutually exclusive exons. (d) The total number of AS events in genes based on Iso-seq data compared with the annotated gene models.