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. 2018 Jul 4;38(9):1679–1689. doi: 10.1007/s00296-018-4095-0

Table 3.

Multivariate analyses for metabolic syndrome-related disease by each stage of VFA and BMI

N = 352 Hypertension (n = 113) Diabetes (n = 29) Dyslipidemia (n = 130) Mean IMT PS
OR Lower CI Upper CI p value OR Lower CI Upper CI p value OR Lower CI Upper CI p value Average (SD) Average (SD)
BMI stage
 BMI-1 (n = 37) 1.00 Reference 1.00 Reference 1.00 Reference 0.67 (0.12) 0.00 (0.00)
 BMI-2 (n = 236) 0.86 0.36 2.20 0.748 1.94 0.34 36.69 0.505 2.11 0.92 5.36 0.080 0.69 (0.17) 0.20 (0.05)
 BMI-3 (n = 79) 4.28 1.63 12.00 0.003 5.56 0.92 108.02 0.063 4.97 1.96 13.67 0.001 0.72 (0.14) 0.33 (0.17)
VFA stage
 VFA-1 (n = 36) 1.00 Reference 1.00 Reference 1.00 Reference 0.66 (0.12) 0.03 (0.03)
 VFA-2 (n = 102) 0.79 0.29 2.26 0.646 0.98 0.12 20.67 0.989 1.13 0.48 2.77 0.774 0.65 (0.12) 0.12 (0.06)
 VFA-3 (n = 117) 1.06 0.41 2.98 0.901 1.60 0.24 31.48 0.661 0.95 0.41 2.30 0.902 0.70 (0.15) 0.14 (0.08)
 VFA-4 (n = 49) 2.04 0.70 6.27 0.193 4.27 0.66 84.33 0.140 1.70 0.65 4.61 0.282 0.72 (0.20) 0.07 (0.05)
 VFA-5 (n = 48) 4.07 1.36 13.06 0.012 6.75 1.07 132.51 0.041 3.76 1.38 10.81 0.009 0.77 (0.19) 0.85 (0.31)

Covariates: age, sex, current smoking (+), average daily physical active level, alcohol intake per week, biologics use, prednisolone use, methotrexate use, and DAS28-ESR

VFA-1; VFA < 25, VFA-2; 25 ≤ VFA < 50, VFA-3; 50 ≤ VFA < 75; VFA-4; 75 ≤ VFA < 100, VFA-5; VFA ≥ 100. BMI-1; BMI < 18.5, BMI-2; 18.5 ≤ BMI < 25, BMI-3; BMI ≥ 25

OR odds ratio, CI 95% confidence interval, SD standard deviation, VFA visceral fat area (cm2), BMI Body Mass Index