Table 5.
Physical function in women with SSRI treatment and matched controls
| Function | SSRI No (n = 344) | SSRI Yes (n = 86) | p-value | Standardized beta | Adjusted p-value |
|---|---|---|---|---|---|
| One leg standing (s) | 14.1 ± 9.3 | 14.3 ± 8.8 | 0.92 | − 0.001 | 0.90 |
| Timed up and go (s) | 8.8 ± 3.6 | 9.3 ± 2.9 | 0.24 | 0.05 | 0.35 |
| Walking speed (m/s) | 1.25 ± 0.25 | 1.17 ± 0.23 | 0.01 | − 0.10 | 0.04 |
| Chair stand test (number/30 s) | 10.9 ± 3.3 | 10.0 ± 3.0 | 0.02 | − 0.11 | 0.03 |
| Grip strength (kg) | 12.9 ± 4.8 | 11.7 ± 4.8 | 0.04 | − 0.09 | 0.08 |
Statistically significant values (p < 0.05) are given in bold
An independent samples t test was used to compare differences in indices of physical function between matched SSRI-users and non-users. Differences in these variables were also investigated in linear regression models adjusted for mental health (MCS). Results for the linear regressions are presented as standardized beta
SSRI selective serotonin reuptake inhibitors