Figure 2.

(Best viewed in color) (a) Bin-level attention weights ( ${\alpha }_t^j$) from AttentiveChrome averaged for all genes when predicting gene=ON and gene=OFF in GM12878 cell type. (b) Top: Cumulative H_active signal across all active genes. Bottom: Plot of the bin-level attention weights ( ${\alpha }_t^j$). These weights are averaged for gene=ON predictions. H_prom weights are concentrated near the TSS and corresponds well with the H_active indicating actual activity near the gene. This indicates that AttentiveChrome is focusing on the correct bin positions for this case (c) Heatmaps visualizing the HM-level weights (β^j), with j ∈ {1, …, 5} for an important differentially regulated gene (PAX5) across three blood lineage cell types: H1-hESC (stem cell), GM12878 (blood cell), and K562 (leukemia cell). The trend of HM-level β^j weights for PAX5 have been verified through biological literature.