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. 2018 Aug 22;4(8):eaat6224. doi: 10.1126/sciadv.aat6224

Fig. 2. H3K9 methyltransferase MET-2/SETDB1 is required for heterochromatin formation.

Fig. 2

(A) TEM of representative nuclei from WT or met-2 embryos. Scale bars, 1 μm. (B) TEM line-scan analysis for WT (black) or met-2 (magenta) nuclei and the SD. Line scan for a single nucleus is shown as an example. (C) Proportion of pixels within EDRs at the 200-cell stage. Error bars denote SEM. (D) Contrast of the cytosol in WT versus met-2 mutants and intensity thresholding (red) to define electron-dense structures. WT nuclei are in green and met-2 nuclei are in magenta.