Table 2.
Comparison of various parameters of LV remodeling between subjects stratified according to HbA1c level adjusted for age, sex, and BMI
| HbA1c (%) |
P value | |||
|---|---|---|---|---|
| ≤6.5 (Group 1) | 6.5–7.5 (Group 2) | >7.5 (Group 3) | ||
| LV mass, g | 131 (114–149) | 158 (141–174) | 152 (134–170) | 0.08 |
| LV mass index | ||||
| By BSA, g/m2 | 62.5 (54.1–70.9) | 74.3 (67.6–80.9) | 68 (60.6–75.5) | 0.12 |
| By height, g/m1.7 | 52.5 (45.1–59.9) | 61.6 (55.7–67.4) | 58.7 (52.1–65.3) | 0.19 |
| Gadolinium partition coefficient (λ) | 0.35 (0.29–0.4) | 0.45 (0.40–0.49) | 0.46 (0.41–0.51) | 0.009*,# |
| ECVF | 21.1 (17.5–24.7) | 27.6 (24.8–30.3) | 27.6 (24.4–30.8) | 0.016*,# |
| Cellular volume, mL | 102 (86–117) | 113 (101–125) | 107 (94–121) | 0.5472 |
| Extracellular volume, mL | 24.7 (19.3–30.2) | 41.4 (34.3–48.5) | 39.3 (31.7–46.9) | <0.001*,# |
| Indexed cellular volume, mL/BSA (m2) | 47.2 (40.8–53.5) | 51 (46–56) | 47.1 (41.5–52.7) | 0.52 |
| Indexed extracellular volume, mL/BSA (m2) | 13 (9.6–16.3) | 20.4 (17.7–23.1) | 18.3 (15.4–21.3) | 0.006* |
Data are mean (95% CI).
*Pairwise comparison between groups 1 and 2 (significant at P < 0.05).
#Pairwise comparison between groups 1 and 3 (significant at P < 0.05).