Skip to main content
. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Oral Pathol Med. 2018 Jun 9;47(7):674–682. doi: 10.1111/jop.12735

Fig. 2. Thymol inhibits Cal27- and HeLa-derived tumor growth in vivo.

Fig. 2

A & D) Tumor volumes of Cal27 (n=6 per group) and HeLa (n=8 per group) xenografts treated with thymol (4.3 mM) every other day for 26 and 22 days respectively. Significant reduction in Cal27-derived tumor volumes is seen by day 16 (* p<0.05) and in HeLa-derived tumor volumes by day 18 (*p<0.05). B & E) Scatter plot of Cal27 and HeLa tumor volumes respectively. Mean tumor volume for Cal27 control tumors is 423 mm3 whereas mean tumor volume for thymol treated Cal27 tumors is 96 mm3. Mean tumor volume for HeLa control tumors is 903 mm3 whereas mean tumor volume for thymol treated HeLa tumors is 537 mm3. C & F) Changes in body weight over the course of the study is shown for tumor-bearing mice with Cal27-derived xenografts (C) and HeLa-derived xenografts (F).