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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Oral Pathol Med. 2018 Jun 9;47(7):674–682. doi: 10.1111/jop.12735

Fig. 6. Thymol inhibits mitochondrial membrane potential and induces apoptosis.

Fig. 6

A) Western blot of c-PARP in Cal27 and HeLa cells treated with increasing concentrations of thymol for 48 h show a dose dependent induction of apoptosis. B & C) Cal27 and HeLa cells, respectively, treated with increasing concentrations of thymol for 2 h show significant reduction in mitochondrial membrane potential as measured by JC-1 aggregate to monomer ratio. D & E) MTS cell viability assays of Cal27 and HeLa cells, respectively, following 48 h treatment demonstrate that 10 nM NAC reverses the anti-proliferative effects of thymol.