Table 1.

Musculoskeletal Infection Society (MSIS) Diagnostic Criteria: 2013–2018 [15]

Major criteria (1 required)	Minor criteria (3 of 5 required)
Sinus tract communicating with the affected joint	Elevated ESR and CRP
	Elevated synovial fluid white blood cell count
Two positive periprosthetic cultures with phenotypically identical organisms	Elevated synovial polymorphonuclear neutrophil percentage (PMN%) or ++ change on leukocyte esterase test strip
	Positive histological analysis of periprosthetic tissue
	A single positive culture

One major criterion and/or 3 of 5 minor criteria must be present for the diagnosis of PJI according to the MSIS Diagnostic Criteria

ESR, erythrocyte sedimentation rate; CRP, C-reactive protein