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. 2018 Aug 22;8:12615. doi: 10.1038/s41598-018-30840-9

Table 1.

Characteristics of the participants at baseline, by categories of medication and healthy lifestyle.

Medication category P Healthy lifestyle category P
0–1 2–4 ≥5 Unfavorable Intermediate Favorable
n 1295 1787 843 665 2308 952
  Women, % 48.8 58.6 63.6 <0.001 57.9 57.4 53.0 0.028
  Age, years 70.7 ± 8.0 72.0 ± 7.8 73.6 ± 7.9 <0.001 75.4 ± 8.5 71.7 ± 7.8 69.9 ± 7.0 <0.001
Educational attainment, %
  No education 48.0 51.1 59.8 64.6 52.6 41.6
  Primary 36.1 36.8 29.9 26.1 34.7 42.2
  Secondary or higher 15.9 12.1 10.3 <0.001 9.4 12.7 16.2 <0.001
Body mass index, kg/m2 28.3 ± 4.1 29.0 ± 4.5 29.6 ± 4.8 <0.001 28.9 ± 5.3 28.9 ± 4.4 28.7 ± 4.0 0.265
Waist circumference, cm 97.3 ± 11.2 98.8 ± 12.1 100.8 ± 12.5 <0.001 99.8 ± 13.9 98.5 ± 11.6 98.6 ± 11.5 0.067
Systolic blood pressure, mm Hg 142.3 ± 18.5 144.1 ± 18.8 142.6 ± 21.0 0.465 144.7 ± 21.0 143.3 ± 19.0 141.8 ± 18.4 0.003
Hypercholesterolemia, % 17.8 25.6 32.6 <0.001 19.4 25.0 27.1 0.001
MMSE, score 25.8 ± 4.3 25.5 ± 4.5 24.9 ± 4.5 <0.001 23.6 ± 5.4 25.5 ± 4.4 26.6 ± 3.3 <0.001
Agility limitations, % 42.5 60.5 79.8 <0.001 76.9 59.3 44.5 <0.001
Mobility limitations, % 34.7 52.2 73.9 <0.001 75.7 50.9 34.2 <0.001
Chronic lung disease, % 7.0 14.5 25.4 <0.001 19.5 15.0 9.1 <0.001
Cardiovascular disease*, % 2.1 7.6 21.1 <0.001 13.7 8.3 6.1 <0.001
Diabetes, % 4.9 15.7 30.4 <0.001 19.1 14.5 14.7 0.065
Cancer, % 1.3 1.8 2.5 0.058 2.2 1.9 1.3 0.744
Depression, % 3.4 10.7 20.1 <0.001 15.3 10.4 6.7 <0.001

Values are means ± SD or %. MMSE: Mini-Mental State examination.