Fig. 4.

Detailed interactions of MRJP1 and apisimin in the MRJP1 dimer. a Overview of the three protein interfaces. Details of the symmetric intermolecular C-terminal and N-terminal interactions (b) and intermolecular C-terminal antiparallel β-sheets β31 (c), and their interactions (d) between MRJP1 protomers were calculated by Ligplot⁷⁰. Hemispheres represent hydrophobic interactions, and lines represent polar interactions. Residues from the two protomers are shown on the left and right, respectively. All residues involved in the hydrophobic interactions are shown in black. For hydrophilic interactions, residues are shown in red or blue. e Details of the interactions of apisimin