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Mean (±SD) plasma concentration-versus-time profile of cefepime (filled circles) and zidebactam (open circles) with the first (A) and seventh (B) doses of WCK 5222 (2 g cefepime/1 g zidebactam) administered as a 1-h intravenous infusion every 8 h. The shaded regions represent the 1-h infusion period. The y axes are in log scale.
