TABLE 3.

Mouse survival at 96 h with different treatments in the in vivo efficacy studies

Isolate	MIC (mg/liter)			Survival (%)
	Plazomicin	Meropenem	Tigecycline	Controls	Plazomicin	Meropenem	Tigecycline	Plazomicin + meropenem	Plazomicin + tigecycline
K. pneumoniae 557	2	8	0.5	0	60	80	0	60	80
K. pneumoniae 558	2	>32	1	10	100	10	30	80	100
Escherichia coli 471	4	0.03	≤0.06	0	100	90	70	70	80
Klebsiella oxytoca 92	4	≤0.015	0.12	10	80	90	80	90	90
Citrobacter freundii 38	4	0.06	0.5	20	90	100	60	100	100
Morganella morganii 65	8	0.06	1	0	70	80	0	100	80
K. pneumoniae 561	8	>32	2	0	20	0	10	100	90
K. pneumoniae 559	16	>32	2	0	70	10	0	70	80