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MICs of Bac5(1-25), Bac5(1-31), and erythromycin for erythromycin-resistant E. coli strains
| Antimicrobial | MICa (μM) |
||||||
|---|---|---|---|---|---|---|---|
| AB301 (wt) | AB301 N281 (L22) | AB301 N282 (L4) | SQ110 ΔtolC (wt) | SQ110 ΔtolC A2059C | SQ110 ΔtolC A2059G | SQ110 ΔtolC A2503C | |
| Bac5(1-25) | 8 | 4–8 | 16 | 1 | 1–2 | 1 | 4 |
| Bac5(1-31) | 8 | 8 | 8 | 2–4 | 4–8 | 4 | 8 |
| Erythromycin | 128 | 1,024 | 1,024 | 2 | 4,096 | 2,048 | 2,048 |
Data are the mode from at least three independent experiments. wt, wild type.
