Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of serine β-lactamases in biochemical assays
| β-Lactamase | Ki (μM) |
|---|---|
| CTX-M-9 | 0.089a |
| CTX-M-14 | 0.085 ± 0.02 |
| CTX-M-27 | 0.28 ± 0.09 |
| CTX-M-15 | 0.25 ± 0.02 |
| CTX-M-14 S237A | 1.23 ± 0.27 |
| TEM-1 | No inbb |
| SHV-2 | 25.8 ± 1.9 |
| KPC-2 | 97.3 ± 1.7 |
| AmpC | 386.9 ± 43.3 |
| OXA-48 | 478.3 ± 166.6 |
As previously reported in reference 12.
No inb, no inhibition.
