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. 2018 Jul 27;62(8):e00283-18. doi: 10.1128/AAC.00283-18

TABLE 2.

MICs of rifabutin in combination with clarithromycin and tigecycline

Strain Median MIC (mg/liter)a
Rifabutin + clarithromycin
Rifabutin + tigecycline
Alone
In combination
Alone
In combination
RFB CLR RFB CLR FICI RFB TGC RFB TGC FICI
ATCC 19977 6.3 0.2 1.6 0.05 0.5 6.3 0.8 1.6 0.4 0.75
Strain 1 6.3 0.4 1.6 0.1 0.5 6.3 1.6 1.6 0.4 0.5
Strain 2 6.3 0.2 1.6 0.05 0.5 6.3 0.8 1.6 0.4 0.75
Strain 3 6.3 0.4 1.6 0.2 0.75 6.3 0.8 3.1 0.2 0.75
Strain 4 6.3 0.4 1.6 0.2 0.75 6.3 0.8 1.6 0.2 0.5
Strain 5 6.3 0.4 1.6 0.1 0.5 6.3 0.8 1.6 0.2 0.5
Strain 6 6.3 0.4 0.8 0.2 0.63 6.3 1.6 1.6 0.8 0.75
a

RFB, rifabutin; CLR, clarithromycin; TGC, tigecycline. Values are the medians of three experiments.