TABLE 2.
Strain | Median MIC (mg/liter)a |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Rifabutin + clarithromycin |
Rifabutin + tigecycline |
|||||||||
Alone |
In combination |
Alone |
In combination |
|||||||
RFB | CLR | RFB | CLR | FICI | RFB | TGC | RFB | TGC | FICI | |
ATCC 19977 | 6.3 | 0.2 | 1.6 | 0.05 | 0.5 | 6.3 | 0.8 | 1.6 | 0.4 | 0.75 |
Strain 1 | 6.3 | 0.4 | 1.6 | 0.1 | 0.5 | 6.3 | 1.6 | 1.6 | 0.4 | 0.5 |
Strain 2 | 6.3 | 0.2 | 1.6 | 0.05 | 0.5 | 6.3 | 0.8 | 1.6 | 0.4 | 0.75 |
Strain 3 | 6.3 | 0.4 | 1.6 | 0.2 | 0.75 | 6.3 | 0.8 | 3.1 | 0.2 | 0.75 |
Strain 4 | 6.3 | 0.4 | 1.6 | 0.2 | 0.75 | 6.3 | 0.8 | 1.6 | 0.2 | 0.5 |
Strain 5 | 6.3 | 0.4 | 1.6 | 0.1 | 0.5 | 6.3 | 0.8 | 1.6 | 0.2 | 0.5 |
Strain 6 | 6.3 | 0.4 | 0.8 | 0.2 | 0.63 | 6.3 | 1.6 | 1.6 | 0.8 | 0.75 |
RFB, rifabutin; CLR, clarithromycin; TGC, tigecycline. Values are the medians of three experiments.