TABLE 4.
3D checkerboard results for a combination of rifabutin, clarithromycin, and tigecycline
| Strain | Median MIC (mg/liter)a |
||||||
|---|---|---|---|---|---|---|---|
| Alone |
In combination |
||||||
| RFB | CLR | TGC | RFB | CLR | TGC | FICI | |
| ATCC 19977 | 6.3 | 0.2 | 0.8 | 0.8 | 0.025 | 0.1 | 0.375 |
| Strain 1 | 6.3 | 0.4 | 1.6 | 0.8 | 0.05 | 0.2 | 0.375 |
| Strain 2 | 6.3 | 0.2 | 0.8 | 0.8 | 0.05 | 0.2 | 0.625 |
| Strain 3 | 6.3 | 0.4 | 0.8 | 0.8 | 0.05 | 0.2 | 0.5 |
| Strain 4 | 6.3 | 0.4 | 0.8 | 0.8 | 0.05 | 0.2 | 0.5 |
| Strain 5 | 6.3 | 0.4 | 0.8 | 0.8 | 0.1 | 0.2 | 0.625 |
| Strain 6 | 6.3 | 0.4 | 1.6 | 0.8 | 0.1 | 0.2 | 0.5 |
a
RFB, rifabutin; CLR, clarithromycin; TGC, tigecycline. Values are the medians of three experiments.