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Regulation of PGLYRP2 and hBD2 expression in oral epithelial cells by IL-17 and IL-22. (A to D) TIGK cells were stimulated with IL-17A (100 ng/ml) (A and B) or IL-22 (50 ng/ml) (C and D) for the times indicated. PGLYRP2 (A and C) and hBD2 (B and D) mRNA levels were then measured (n = 3). (E and F) TIGK cells were stimulated with IL-17A (100 ng/ml) and IL-22 (50 ng/ml) for 24 h. PGLYRP2 (E) and hBD2 (F) mRNA levels were then measured (n = 3). ***, P < 0.001; **, P < 0.01; *, P < 0.05.
