FIG 10.

Deletion of ohr or ohrR differentially affects survival on exposure to organic hydroperoxides in vitro and killing of C. elegans. Ovals represent ΔohrR, WT, and Δohr cells in which the levels of organic hydroperoxide (OHP) are low, medium, and high, respectively (colored bar graphs), as determined by the FOX assay (Fig. 7). Genes in the OHP and/or OhrR regulons (including ohr, in the case of WT cells) are expected to be the most efficiently induced in WT and Δohr cells. Boxes below the ovals represent items that may promote (+) or counter (−) survival on exposure to OHP in vitro and C. elegans killing. n/a, not applicable.