TABLE 4.
Odds ratios for the influence of antibodies to FV2 and merozoite antigens on pregnancy outcome in PM+ womena
| Antigen | OR (95% CI) |
|||
|---|---|---|---|---|
| Anemia | High placental parasitemia | LBW | Preterm delivery | |
| FV2 | 0.726 (0.429, 1.229) | 0.432 (0.272, 0.687)* (P = 0.0004) | 0.444 (0.247, 0.799)* (P = 0.0068) | 0.590 (0.335, 1.040) |
| MSP142 | 1.408 (0.768, 2.583) | 1.367 (0.828, 2.257) | 0.873 (0.468, 1.632) | 1.210 (0.641, 2.283) |
| MSP2 | 0.608 (0.289, 1.278) | 0.538 (0.272, 1.063) | 0.546 (0.256, 1.163) | 0.720 (0.329, 1.572) |
| MSP3 | 0.727 (0.405, 1.304) | 0.593 (0.361, 0.974) (P = 0.0389) | 1.268 (0.680, 2.363) | 0.927 (0.494, 1.737) |
| MSP11 | 0.653 (0.317, 1.346) | 1.197 (0.679, 2.108) | 1.547 (0.767, 3.123) | 2.168 (1.114, 4.222) |
| AMA1 | 0.777 (0.180, 3.354) | 0.216 (0.046, 1.019) | 0.990 (0.197, 4.981) | 0.410 (0.103, 1.636) |
| EBA-175 | 0.690 (0.307, 1.553) | 0.444 (0.214, 0.920) (P = 0.0291) | 0.575 (0.263, 1.257) | 0.406 (0.188, 0.873) (P = 0.0211) |
| Pf41 | 0.685 (0.409, 1.149) | 0.486 (0.309, 0.765)* (P = 0.0018) | 0.832 (0.471, 1.469) | 0.722 (0.414, 1.257) |
a
ORs with 95% CIs reported were based on logistic models, adjusted for age and gravidity. The 95% CIs of ORs reaching outside 1.0 (highlighted in bold) were statistically significant. *, statistically significant ORs after Bonferroni correction for multiple comparisons among four pregnancy outcomes.