Table 1. Summary of individual EGFR mutation types (including multiple mutations).
| EGFR mutations | N | % |
|---|---|---|
| Patients with an evaluable EGFR mutation test | 1,001 | 100 |
| Sensitizing mutations alone | 189 | 18.9 |
| Exon 19 deletion | 89 | 8.9 |
| Exon 21 L858R | 86 | 8.6 |
| Exon 21 L861Q | 3 | 0.3 |
| Exon 20 S768I | 1 | 0.1 |
| Exon 18 G719X | 10 | 1.0 |
| Combination of sensitizing mutations | 3 | 0.3 |
| L858R + 19del | 1 | 0.1 |
| L858R + S768I | 1 | 0.1 |
| G719X + S768I | 1 | 0.1 |
| Resistance mutations alone | 28 | 2.8 |
| Exon 20 T790M | 21 | 2.1 |
| Exon 20 insertion | 7 | 0.7 |
| Combination of sensitizing and resistance mutations | 31 | 3.1 |
| 19del + T790M | 18 | 1.8 |
| L858R + T790M | 12 | 1.2 |
| L858R + 20ins | 1 | 0.1 |
| Patients with a negative EGFR mutation test | 750 | 74.9 |
EGFR, epidermal growth factor receptor.