Table S1. Comparison of clinical characteristics for chemotherapy-naïve and -treated patients.
| Clinical factors | Chemotherapy-naive | Chemotherapy-treated | P |
|---|---|---|---|
| Age, years | <0.001 | ||
| Median | 68 | 65 | |
| Range | 33–94 | 19–82 | |
| Gender, n (%) | 0.006 | ||
| Male | 457 (58.3) | 149 (68.7) | |
| Female | 327 (41.7) | 68 (31.3) | |
| Smoking history, n (%) | 0.023 | ||
| Never | 451 (57.5) | 106 (48.8) | |
| Former/current | 333 (42.5) | 111 (51.2) | |
| Histology, n (%) | <0.001 | ||
| Adenocarcinoma | 694 (88.5) | 174 (80.2) | |
| Non-adenocarcinoma | 90 (11.5) | 43 (19.8) | |
| Tumor stage, n (%) | <0.001 | ||
| III | 289 (36.9) | 52 (24.0) | |
| IV | 495 (63.1) | 165 (76.0) | |
| Organs with metastases, n (%) | <0.001 | ||
| 0 | 434 (55.4) | 89 (41.0) | |
| 1 | 245 (31.3) | 90 (41.5) | |
| 2 or more | 105 (13.4) | 38 (17.5) |