Table 1. Drugs down-modulating MDSC in cancer.
Class | Drug |
---|---|
Chemotherapeutics | Anthracyclines |
Cisplatin | |
Taxane | |
Vinorelbine | |
Gemcitabine | |
Anti-angiogenics | Dasatinib |
Ibrutinib | |
Bevacizumab | |
Sunitinib | |
Targeted therapies | Erlotinib |
Brentuximab | |
Physical therapies | Radiotherapy |
Novel MDSC targeting drugs | IDO inhibitor |
ROS-iNOS inhibitors | |
TGF-β inhibitor | |
CSF1R inhibitor |
MDSC, myeloid-derived suppressor cells.