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. 2018 Jul;10(7):4619–4631. doi: 10.21037/jtd.2018.07.30

Table 1. Drugs down-modulating MDSC in cancer.

Class Drug
Chemotherapeutics Anthracyclines
Cisplatin
Taxane
Vinorelbine
Gemcitabine
Anti-angiogenics Dasatinib
Ibrutinib
Bevacizumab
Sunitinib
Targeted therapies Erlotinib
Brentuximab
Physical therapies Radiotherapy
Novel MDSC targeting drugs IDO inhibitor
ROS-iNOS inhibitors
TGF-β inhibitor
CSF1R inhibitor

MDSC, myeloid-derived suppressor cells.