Table 1. Patients’ characteristics, treatments, pathology findings, and outcome according to the kind of surgery.
| Variables | All | Thymomectomy | Radical thymectomy | P |
|---|---|---|---|---|
| No. of patients | 157 (100%) | 86 (54.8%) | 71 (45.2%) | – |
| Age | 57±14 | 58±14 | 56±14 | 0.202 |
| Gender (males), n (%) | 76 (48.4) | 41 (47.7) | 35 (49.3) | 0.873 |
| MG, n (%) | 22 (14.0) | 0 | 22 (31.0) | <0.001 |
| Charlson index | 1.78±1.60 | 2.00±1.67 | 1.49±1.47 | 0.073 |
| WHO predominant histology, n (%) | 0.055 | |||
| A | 21 (13.4) | 10 (11.6) | 11 (15.5) | |
| AB | 45 (28.7) | 32 (37.2) | 13 (18.3) | |
| B1 | 27 (17.2) | 12 (14.0) | 15 (21.1) | |
| B2 | 22 (14.0) | 12 (14.0) | 10 (14.1) | |
| B3 | 27 (17.2) | 10 (11.6) | 17 (23.9) | |
| Carcinoma | 15 (9.6) | 10 (11.6) | 5 (7.0) | |
| Masaoka stage, n (%) | 0.724 | |||
| I | 41 (26.1) | 20 (23.3) | 21 (29.6) | |
| II | 74 (47.1) | 44 (51.2) | 30 (42.3) | |
| III | 29 (18.5) | 15 (17.4) | 14 (19.7) | |
| IV | 13 (8.3) | 7 (8.1) | 6 (8.5) | |
| Incomplete resection, n (%) | 16 (10.2) | 9 (10.5) | 7 (9.9) | 1.000 |
| R1 resection | 10 (6.4) | 6 (7.0) | 4 (5.6) | |
| R2 resection | 6 (3.8) | 3 (3.5) | 3 (4.2) | |
| Approach, n (%) | 0.944 | |||
| Open | 123 (78.3) | 68 (79.1) | 55 (77.5) | |
| VATS | 29 (18.5) | 15 (17.4) | 14 (19.7) | |
| Conversion | 5 (3.2) | 3 (3.5) | 2 (2.8) | |
| Extended surgery, n (%) | 55 (35.0) | 27 (31.4) | 28 (39.4) | 0.317 |
| Complications, n (%) | 33 (21.0) | 15 (17.4) | 18 (25.4) | 0.243 |
| Post-operative stay | 5 [0–30] | 5 [2–28] | 5 [0–30] | 0.227 |
| Multimodality therapy, n (%) | 50 (31.8) | |||
| Neoadjuvant chemo | 17 (10.8) | 10 (11.6) | 7 (9.9) | 0.800 |
| Neoadjuvant RT | 3 (1.9) | 2 (2.3) | 1 (1.4) | 1.000 |
| Adjuvant chemo | 11 (7.0) | 6 (7.0) | 5 (7.0) | 1.000 |
| Adjuvant RT (PORT) | 36 (22.9) | 20 (23.3) | 16 (22.5) | 1.000 |
WHO, World Health Organization; VATS, video-assisted thoracic surgery; RT, radiotherapy; PORT, post-operative radiotherapy.