Table. Analysis of a Batai virus–infected harbor seal with meningoencephalomyelitis, Germany, 2016*.

Sample material	Histopathologic finding	Real-time PCR (cycle threshold)†	FISH
Brain	Cerebrum, cerebellum, brain stem, medulla oblongata, and cervical spinal cord: mild to moderate, multifocal, and lymphohistiocytic meningoencephalomyelitis, perivascularly accentuated; parietal lobe: multiple glial nodules; thoracic spinal cord: mild to moderate and multifocal meningitis, perivascularly accentuated, lymphohistiocytic with few eosinophilic granulocytes; cauda equina: mild to moderate, multifocal, and lymphohistiocytic perineuritis	+ (15)	+
Lung	Mild and multifocal anthracosis; acute, diffuse, and severe hyperemia; acute, diffuse, and moderate edema	– (>35)	–
Spleen	Moderate to severe and diffuse hyperemia	– (35)	–
Kidney	Mild, interstitial, and lymphohistiocytic nephritis with single, intratubular concrements	– (>35)	–
Pulmonary lymph node	Mild follicular hyperplasia	NI	­+
Mesenteric lymph node	Mild to moderate follicular hyperplasia and hemosiderosis	NI	–
Liver	Mild, multifocal, lymphohistiocytichepatitis, mild to moderate hepatocellular storage of iron	– (>35)	–
Small intestine	Mild, diffuse, lymphoplasmacytic, and partially eosinophilic enteritis	+ (28)	+
Large intestine	NSML	NI	–
Nose	NSML	NI	–
Heart	NSML	NI	–
Stomach	NSML	NI	–

*FISH, fluorescent in situ hybridization; NI, not investigated; NSML, no major microscopic lesions; –, negative; +, positive.
†Negative result >35; positive result <35.