Table 3.
The 32 major targets information of Qingdai.
| ID | Target | Uniprot ID | Gene name | PDB ID |
|---|---|---|---|---|
| MT-1 | Mitogen-activated protein kinase 8 | P45983 | MAPK8 | IUKH |
| MT-2 | Estrogen receptor | P03372 | ESR1 | 1A52 |
| MT-3 | Mitogen-activated protein kinase 14 | Q16539 | MAPK14 | 1A9U |
| MT-4 | Cyclin-dependent kinase 2 | P24941 | CDK2 | 1AQ1 |
| MT-5 | Vascular endothelial growth factor receptor 2 | P35968 | KDR | 1VR2 |
| MT-6 | Cyclin-dependent kinase 4 | P11802 | CDK4 | 2W96 |
| MT-7 | Androgen receptor | P10275 | AR | 1E3G |
| MT-8 | Prothrombin | P00734 | F2 | 1A2C |
| MT-9 | Cyclin-dependent kinase 1 | P06493 | CDK1 | 4Y72 |
| MT-10 | Glycogen synthase kinase-3 beta | P49841 | GSK3B | 1GNG |
| MT-11 | Platelet-derived growth factor receptor beta | P09619 | PDGFRB | 1GQ5 |
| MT-12 | Mitogen-activated protein kinase 9 | P45984 | MAPK9 | 3E7O |
| MT-13 | G2/mitotic-specific cyclin-B1 | P14635 | CCNB1 | 2B9R |
| MT-14 | Mitogen-activated protein kinase 11 | Q15759 | MAPK11 | 3GC8 |
| MT-15 | Receptor-type tyrosine-protein kinase FLT3 | P36888 | FLT3 | 1RJB |
| MT-16 | Cyclin-dependent kinase 6 | Q00534 | CDK6 | 1BI7 |
| MT-17 | Vascular endothelial growth factor receptor 1 | P17948 | FLT1 | 1FLT |
| MT-18 | Toll-like receptor 9 | Q9NR96 | TLR9 | 3WPB |
| MT-19 | Cyclin-dependent-like kinase 5 | Q00535 | CDK5 | 1H4L |
| MT-20 | C-C chemokine receptor type 5 | P51681 | CCR5 | 4MBS |
| MT-21 | Alpha-synuclein | P37840 | SNCA | 2X6M |
| MT-22 | Low-density lipoprotein receptor | P01130 | LDLR | 1AJJ |
| MT-23 | Estrogen receptor beta | Q92731 | ESR2 | 1L2J |
| MT-24 | Glycogen synthase kinase-3 alpha | P49840 | GSK3A | 2DFM |
| MT-25 | Aromatase | P11511 | CYP19A1 | 3EQM |
| MT-26 | Platelet-derived growth factor receptor alpha | P16234 | PDGFRA | 5GRN |
| MT-27 | Mitogen-activated protein kinase 10 | P53779 | MAPK10 | 1JNK |
| MT-28 | C-C chemokine receptor type 2 | P41597 | CCR2 | 5T1A |
| MT-29 | Cyclin-dependent kinase 3 | Q00526 | CDK3 | ILFN |
| MT-30 | Microtubule-associated protein tau | P10636 | MAPT | 2ON9 |
| MT-31 | ATP-binding cassette sub-family G member 2 | Q9UNQ0 | ABCG2 | 5NJ3 |
| MT-32 | Vascular endothelial growth factor receptor 3 | P35916 | FLT4 | 4BSJ |