Table 5.
Obtained results from validation of the proposed method: robustness.
| Simvastatin | Res E/F | Res G/SIM | Res B/C | |||
|---|---|---|---|---|---|---|
| Rt (min) | T | NTP | ||||
| Flow (mL/min) | ||||||
| 0.6 mL/min | 14.05 | 0.99 | 109188 | 1.52 | 4.48 | 1.66 |
| 0.8 mL/min | 13.78 | 1.08 | 128239 | 1.50 | 4.46 | 1.53 |
| Content of acetonitrile in initial phase | ||||||
| 35% | 14.77 | 1.05 | 234052 | 1.53 | 4.05 | 1.61 |
| 45% | 14.74 | 1.02 | 236896 | 1.58 | 4.17 | 1.66 |
| Column temperature | ||||||
| 30°C | 13.42 | 1.01 | 93614 | 1.51 | 4.68 | 1.89 |
| 40°C | 13.83 | 1.02 | 109994 | 1.53 | 4.43 | 1.78 |
| Another column | 15.07 | 1.05 | 169635 | 1.59 | 4.47 | 2.15 |