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Neural circuitry and brain regions involved in itch. Different types of neuropathic itch have been found to arise from lesions at different levels of the pathway. Abbrevions: ACC: anterior cingulate cortex; PFC: prefrontal cortex; SI: primary somatosensory cortex; SII: secondary somatosensory cortex; PBn: parabrachial nucleus; PAG: periaqueductal gray; DRG: dorsal root ganglia
