Table 2.
DC-SIGN gene polymorphisms | Population/Country | Allele/haplotype | Association | Sample size | References | |
---|---|---|---|---|---|---|
HCs | TB | |||||
−871(A/G)−336(A/G) | South African | −871G −336A | Protection | 360 | 351 | (187) |
−939(G/A) | Indonesian Vietnamese | GG vs. GA+AA | Protection No association | (188) | ||
−336(A/G) | South Indian | −336GG | Susceptibility to PTB in HIV | 157 | 107 | (189) |
African | −336G | Protection | 914 | 1,262 | (190) | |
Asian | −336GG | Susceptibility | 3,610 | 3,539 | (191) | |
Asian | −336GG | Susceptibility | 3,088 | 3,114 | (192) | |
−871G | Protection | |||||
−336(A/G) | Spanish | No association | 299 | 110 | (193) | |
DC-SIGNR VNTR | Iranian | No association | 161 | 171 | (194) | |
−336(A/G)139(A/G) | West African | No association | 347 | 321 | (195) | |
−336(A/G) | Chinese | No association | 2614 | 2598 | (196) |
DC-SIGN, Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin.