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. 2018 Aug 16;5:213. doi: 10.3389/fmed.2018.00213

Table 2.

Association of DC-SIGN polymorphisms among different ethnic populations.

DC-SIGN gene polymorphisms Population/Country Allele/haplotype Association Sample size References
HCs TB
−871(A/G)−336(A/G) South African −871G −336A Protection 360 351 (187)
−939(G/A) Indonesian Vietnamese GG vs. GA+AA Protection No association (188)
−336(A/G) South Indian −336GG Susceptibility to PTB in HIV 157 107 (189)
African −336G Protection 914 1,262 (190)
Asian −336GG Susceptibility 3,610 3,539 (191)
Asian −336GG Susceptibility 3,088 3,114 (192)
−871G Protection
−336(A/G) Spanish No association 299 110 (193)
DC-SIGNR VNTR Iranian No association 161 171 (194)
−336(A/G)139(A/G) West African No association 347 321 (195)
−336(A/G) Chinese No association 2614 2598 (196)

DC-SIGN, Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin.