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. 2018 Aug 6;2018:8168720. doi: 10.1155/2018/8168720

Figure 4.

Figure 4

The cIPC-induced improvements in the neurological functional deficit and cerebral infarction induced by MCAO/R are compromised by the γ-secretase inhibitor DAPT. (a) Jagged1, Notch1, NICD, and Hes1 expression levels in the brain tissues of DAPT-treated rats. (b) The neurological functional deficit score was examined to evaluate the effect of DAPT and/or cIPC on the neurological functional deficit induced by MCAO/R. (c-d) TTC staining was conducted to evaluate the effect of DAPT and/or cIPC on cerebral infarction induced by MCAO/R. The top figure is the infarct ratio calculated according to the results of TTC staining (c). The bottom photo is the represented image of TTC staining (d). ∗p < 0.05.