Table 4.

Statistics for the comparison of saliva BDNF methylation in BPD patients before and after therapy

CpG site	Mean difference	CI lower	CI upper	p value	Cohen’s d
CpG11:27723161	− 0.7	− 1.303	− 0.011	0.047	0.4
CpG11:27723159	− 0.6	− 1.562	0.282	0.165	n.a.
CpG11:27723143	− 1.4	− 2.542	− 0.324	0.013	0.5
CpG11:27723137	− 0.0	− 0.660	0.561	0.871	n.a.
Average	− 0.7	− 1.370	− 0.019	0.044	0.4

Results of paired t tests for salivary BDNF IV promoter methylation in BPD patients before (T1) and after treatment (T2) (N = 26). Results shown for individual CpG sites and for the average calculated from all sites

n.a. not applicable (p value > 0.05)