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. 2018 Jun 8;35(9):2145–2158. doi: 10.1093/molbev/msy116

Table 1.

Proportion of Bound Peptides across the Five Classical MHC Loci.

Locus Proportion of Peptides Bound By At Least One Allele Proportion of Bound Peptides Per Allele
Min Max Median (95% CI)
HLA-A 0.185 0.014 0.074 0.017 (0.0159, 0.0178)
HLA-B 0.192 0.012 0.018 0.017 (0.0168, 0.0172)
HLA-C 0.079 0.014 0.019 0.017 (0.0165, 0.0171)
HLA-DRB1 0.025 0.002 0.005 0.003 (0.0026, 0.0031)
HLA-DQB1 0.011 0.001 0.004 0.002 (0.0015, 0.0027)

Note.—MHC allele-specific peptide binding was predicted computationally for each locus. Total number of peptides: 118,097.