Table 1.
Proportion of Bound Peptides across the Five Classical MHC Loci.
Locus | Proportion of Peptides Bound By At Least One Allele | Proportion of Bound Peptides Per Allele |
||
---|---|---|---|---|
Min | Max | Median (95% CI) | ||
HLA-A | 0.185 | 0.014 | 0.074 | 0.017 (0.0159, 0.0178) |
HLA-B | 0.192 | 0.012 | 0.018 | 0.017 (0.0168, 0.0172) |
HLA-C | 0.079 | 0.014 | 0.019 | 0.017 (0.0165, 0.0171) |
HLA-DRB1 | 0.025 | 0.002 | 0.005 | 0.003 (0.0026, 0.0031) |
HLA-DQB1 | 0.011 | 0.001 | 0.004 | 0.002 (0.0015, 0.0027) |
Note.—MHC allele-specific peptide binding was predicted computationally for each locus. Total number of peptides: 118,097.