Table 2.
Changes in anthropometric and lipid levels associated with randomization to calorie restriction diets.
| Control | Calorie restriction
|
P value
|
|||||
|---|---|---|---|---|---|---|---|
| Daily | Intermittent | Control vs. Daily CRa | Control vs. Intermittent CRb | Control vs. Either CRc | Daily vs. Intermittentd | ||
| Anthropometrice | |||||||
| Δ weight, kg/week | −0.17 (−0.34–0.00) | −0.53 (−0.69–−0.38) | −0.32 (−0.48–−0.17) | 0.003 | 0.21 | 0.02 | 0.15 |
| Δ BMI, kg/m2 per week | −0.05 (−0.11–0.01) | −0.19 (−0.24–−0.13) | −0.11 (−0.17–−0.06) | 0.003 | 0.15 | 0.01 | 0.15 |
| Δ waist circumference, cm/week | −0.18 (−0.67–0.31) | −0.24 (−0.70–0.21) | −0.20 (−0.64–0.23) | 0.86 | 0.94 | 0.89 | 0.41 |
| Δ hip circumferences, cm/week | −0.16 (−0.41–0.10) | −0.35 (−0.58–−0.11) | −0.48 (−0.71–0.25) | 0.07 | 0.30 | 0.09 | 0.41 |
| Δ Lean mass, g/week | −50.2 (−169.9–−50.2) | −144.6 (−253.0–−36.2) | −157.6 (−266.0–−49.3) | 0.26 | 0.21 | 0.17 | 0.96 |
| Δ Fat mass, g/week | −164.5 (−292.4–−36.6) | −330.1 (−445.8–−214.5) | −119.8 (−235.5–−4.2) | 0.07 | 0.62 | – | 0.03 |
| Δ VAT mass, g/week | 2.2 (−9.6–14.0) | −9.0 (−19.8–1.8) | −6.4 (−17.2–4.4) | 0.26 | 0.21 | 0.15 | 0.57 |
| %Δ in total body fat/week | −0.08 (−0.20–0.04) | −0.14 (−0.26–−0.03) | 0.00 (−0.12–0.10) | 0.52 | 0.37 | 0.88 | 0.12 |
| %Δ VAT of total fat/week | 0.01 (−0.01–0.03) | −0.005 (−0.02–0.01) | −0.01 (−0.03–0.01) | 0.17 | 0.06 | 0.05 | 0.77 |
| Fasting glucose mg/dL/week | 0.42 (−0.38–1.22) | −0.71 (−1.47–0.05) | −0.11 (−0.90–0.69) | 0.06 | 0.31 | 0.09 | 0.49 |
| Lipids | |||||||
| Δ triglycerides, mg/dL per week | −0.58 (−2.70–1.54) | −1.05 (−3.04–0.84) | −1.69 (−3.78–0.39) | 0.75 | 0.47 | 0.53 | 0.63 |
| Δ total cholesterol, mg/dL per week | −1.25 (−2.87–0.37) | −1.35 (−2.84–0.14) | −2.34 (−0.39–−3.90) | 0.93 | 0.35 | 0.55 | 0.60 |
| Δ HDL cholesterol, mg/dL per week | −0.46 (−1.15–0.22) | −0.61 (−1.24–0.04) | −0.72 (−1.39–−0.05) | 0.78 | 0.62 | 0.65 | 0.91 |
| Δ LDL cholesterol, mg/dL per week | −0.66 (−1.89–0.57) | −0.55 (−1.69–0.57) | −1.27 (−2.45–−0.09) | 0.91 | 0.49 | 0.74 | 0.52 |
a
Test for differential change between daily CR vs. control diet.
b
Test for differential change between intermittent CR vs. control diet.
c
Test for differential change between any CR relative to control diet.
d
Test for differential change between daily vs. intermittent CR relative to control.
e
Values displayed are rate of change per week over the 8-week study period.