Table 2. Incidence rates for hemorrhagic stroke, subdural hemorrhage, subarachnoid hemorrhage and traumatic intracranial hemorrhage by drug exposure group.

Antithrombotic treatment	Hemorrhagic stroke			Subdural hemorrhage			Subarachnoid hemorrhage			Traumatic intracranial hemorrhage
	Events, No.	Crude Rate, Events per 100 Person-Years (95% CI)	Age and sex adjusted incidence rate, Events per 100 Person-Years (95% CI)	Events, No.	Crude Rate, Events per 100 Person-Years (95% CI)	Age and sex adjusted incidence rate, Events per 100 Person-Years (95% CI)	Events, No.	Crude Rate, Events per 100 Person-Years (95% CI)	Age and sex adjusted incidence rate, Events per 100 Person-Years (95% CI)	Events, No.	Crude Rate, Events per 100 Person-Years (95% CI	Age and sex adjusted incidence rate, Events per 100 Person-Years (95% CI)
None	4967	0.027 (0.026–0.028)	0.034 (0.034–0.035)	2701	0.015 (0.014–0.015)	0.019 (0.019–0.020)	2076	0.011 (0.011–0.012)	0.012 (0.011–0.012)	4312	0.023 (0.023–0.024)	0.027 (0.026–0.028)
Aspirin	2103	0.11 (0.10–0.11)	0.053 (0.040–0.066)	967	0.048 (0.045–0.052)	0.021 (0.018–0.025)	399	0.020 (0.018–0.022)	0.015 (0.011–0.018)	1232	0.062 (0.058–0.065)	0.033 (0.027–0.040)
Warfarin	813	0.27 (0.25–0.28)	0.12 (0.099–0.15)	454	0.15 (0.13–0.16)	0.076 (0.058–0.093)	77	0.025 (0.020–0.031)	0.024 (0.013–0.034)	334	0.11 (0.098–0.12)	0.051 (0.041–0.061)
Aspirin plus Clopidogrel	83	0.11 (0.09–0.14)	0.049 (0.036–0.062)	77	0.11 (0.084–0.13)	0.069 (0.034–0.10)	24	0.033 (0.021–0.049)	0.019 (0.0096–0.028)	80	0.11 (0.087–0.14)	0.060 (0.043–0.076)
Aspirin-Dipyridamole	317	0.24 (0.21–0.27)	0.13 (0.088–0.18)	112	0.085 (0.070–0.10)	0.029 (0.023–0.036)	68	0.052 (0.040–0.065)	0.033 (0.019–0.047)	153	0.12 (0.098–0.14)	0.099 (0.0050–0.19)
Warfarin plus Aspirin	132	0.38 (0.32–0.45)	0.19 (0.12–0.25)	69	0.20 (0.15–0.25)	0.096 (0.051–0.14)	10	0.029 (0.014–0.052)	0.011 (0.0030–0.020)	52	0.15 (0.11–0.19)	0.049 (0.032–0.067)
Clopidogrel	57	0.13 (0.10–0.17)	0.085 (0.052–0.12)	49	0.11 (0.084–0.15)	0.083 (0.0050–0.16)	10	0.023 (0.011–0.043)	0.011 (0.0035–0.018)	46	0.11 (0.078–0.14)	0.069 (0.038–0.10)
Rivaroxaban	60	0.34 (0.26–0.43)	0.16 (0.11–0.21)	8	0.045 (0.019–0.088)	0.024 (0.0021–0.045)	5	0.028 (0.009–0.065)	0.012 (0.00038–0.023)	18	0.10 (0.060–0.16)	0.065 (0.015–0.12)
Dipyridamole	28	0.26 (0.17–0.37)	0.083 (0.046–0.12)	10	0.092 (0.044–0.17)	0.028 (0.0099–0.046)	1	0.0092 (0.00023–0.051)	0.0024 (-0.0023–0.0070)	10	0.092 (0.044–0.17)	0.040 (0.0033–0.077)
Dabigatran	21	0.13 (0.08–0.20)	0.044 (0.024–0.063)	9	0.056 (0.025–0.11)	0.022 (0.0062–0.039)	1	0.0062 (0.00016–0.034)	0.0017 (-0.0016–0.0050)	9	0.056 (0.025–0.11)	0.027 (-0.0013–0.056)
Ticagrelor plus Aspirin	7	0.079 (0.03–0.16)	0.062 (-0.000094–0.12)	6	0.068 (0.025–0.15)	0.059 (-0.0012–0.12)	3	0.034 (0.0070–0.099)	0.016 (-0.0036–0.034)	9	0.10 (0.047–0.19)	0.066 (0.010–0.12)
Apixaban	7	0.26 (0.10–0.54)	0.10 (0.022–0.18)	4	0.15 (0.041–0.38)	0.051 (-0.0038–0.11)	0	0.00 (0.00–0.14)	0.00 (0.00–0.00)	1	0.037 (0.00094–0.21)	0.012 (-0.011–0.035)
Warfarin plus Aspirin and Clopidogrel	9	0.45 (0.20–0.85)	0.26 (0.00077–0.51)	5	0.25 (0.081–0.58)	0.044 (0.0039–0.085)	1	0.050 (0.0013–0.28)	0.012 (-0.012–0.036)	2	0.10 (0.012–0.36)	0.022 (-0.0086–0.052)
Dabigatran plus Aspirin	6	0.24 (0.09–0.53)	0.13 (-0.034–0.29)	2	0.08 (0.0097–0.29)	0.054 (-0.040 to 0.15)	0	0.00 (0.00–0.15)	0.00 (0.00–0.00)	2	0.080 (0.0097–0.29)	0.055 (-0.039–0.15)
Rivaroxaban plus Aspirin	12	0.54 (0.28–0.95)	0.25 (0.069–0.43)	3	0.14 (0.028–0.40)	0.030 (-0.0051–0.065)	1	0.045 (0.0011–0.25)	0.021 (-0020- 0.062)	4	0.18 (0.049–0.46)	0.056 (-0.0046–0.12)
Aspirin-Dipyridamole plus Clopidogrel	5	0.47 (0.15–1.09)	0.19 (0.0071–0.37)	3	0.28 (0.058–0.82)	0.064 (-0.0093–0.14)	0	0.00 (0.00–0.34)	0.00 (0.00–0.00)	6	0.56 (0.21–1.22)	0.19 (0.034–0.34)
Other antithrombotic medication	15	0.38 (0.27–0.52)	0.16 (0.10–0.21)	8	0.080 (0.035–0.16)	0.029 (0.0079–0.050)	4	0.040 (0.011–0.10)	0.024 (0.052–2.43)	9	0.090 (0.041–0.17)	0.040 (0.0084–0.072)

Patients could have multiple treatment courses with one drug or with different drugs.