Table 2. Patient characteristics and sensitivity of the clinical signs.
Elder | Younger | P# | |
---|---|---|---|
Number | 50 | 50 | |
Male/female | 18/32 | 13/37 | |
Mean age (years) | 48.7 ± 11.6 | 72.8 ± 5.8 | |
Diagnosis of ocular sarcoidosis | |||
Presumed | 26 | 39 | |
Probable | 14 | 7 | |
Possible | 10 | 4 | |
Ocular signs | |||
Keratic precipitates/iris nodules | 40% | 64% | 0.012 |
Trabecular meshwork nodules and/or tent-shaped peripheral anterior synechiae | 20% | 28% | 0.19 |
Vitreous opacities displaying snowballs/strings of pearls | 60% | 78% | 0.0059 |
Multiple chorioretinal peripheral lesions | 32% | 36% | 0.55 |
Periphlebitis and/or macroaneurysm | 54% | 58% | 0.57 |
Optic disc nodule and/or choroidal nodule | 10% | 12% | 0.65 |
Bilateral inflammation | 64% | 80% | 0.012 |
Laboratory investigations | |||
Negative tuberculin purified | 88% | 80% | 0.12 |
Elevated serum ACE and/or lysozyme | 26% | 36% | 0.13 |
Bilateral hilar lymphadenopathy | 52% | 78% | <0.001 |
Elevated liver enzyme tests | 30% | 34% | 0.54 |
#: analysed by 2 × 2 chi-squared test and Fischer’s exact test