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. 2018 Aug 23;13(8):e0202585. doi: 10.1371/journal.pone.0202585

Table 2. Patient characteristics and sensitivity of the clinical signs.

Elder Younger P#
Number 50 50
Male/female 18/32 13/37
Mean age (years) 48.7 ± 11.6 72.8 ± 5.8
Diagnosis of ocular sarcoidosis
 Presumed 26 39
 Probable 14 7
 Possible 10 4
Ocular signs
Keratic precipitates/iris nodules 40% 64% 0.012
 Trabecular meshwork nodules and/or tent-shaped peripheral anterior synechiae 20% 28% 0.19
 Vitreous opacities displaying snowballs/strings of pearls 60% 78% 0.0059
 Multiple chorioretinal peripheral lesions 32% 36% 0.55
 Periphlebitis and/or macroaneurysm 54% 58% 0.57
 Optic disc nodule and/or choroidal nodule 10% 12% 0.65
 Bilateral inflammation 64% 80% 0.012
Laboratory investigations
 Negative tuberculin purified 88% 80% 0.12
 Elevated serum ACE and/or lysozyme 26% 36% 0.13
 Bilateral hilar lymphadenopathy 52% 78% <0.001
 Elevated liver enzyme tests 30% 34% 0.54

#: analysed by 2 × 2 chi-squared test and Fischer’s exact test