Table 3. Comparison of clinical characteristics between the DAS and US remission groups and the non-remission groups at 12 weeks.
| DAS | US | |||||
|---|---|---|---|---|---|---|
| Characteristics | Rem (n = 20) | Non-rem (n = 23) | P | Rem (n = 11) | Non-rem (n = 31) | P |
| CRP (mg/dL) | 0.04 (0.02–0.13) | 0.12 (0.05–0.13) | 0.022* | 0.04 (0.01–0.07) | 0.1 (0.03–0.53) | 0.030* |
| ESR (mm/h) | 6 (4.3–10.8) | 18 (9–36) | 0.0001** | 6 (4–11) | 14 (7–23) | 0.010* |
| Serum MMP-3 (ng/mL) | 69.2 (39.9–119.1) | 102 (63.3–204) | 0.064 | 51 (31.1–76.7) | 102 (63.3–196.6) | 0.0078* |
| DAS28ESR | 2.26 (1.59–2.71) | 4.11 (3.38–4.45) | <0.0001*** | 2.56 (1.25–3.15) | 3.50 (2.22–4.43) | 0.020* |
| CDAI | 5.5 (4.1–8.3) | 13.3 (9.4–17.7) | <0.0001*** | 7 (4–9.8) | 10 (5.1–15.4) | 0.10 |
| Total GS score | 14 (8–16) | 11 (8–14) | 0.34 | 9 (8–16) | 12 (9–16) | 0.34 |
| Total PD score | 4 (3–7) | 6 (4–10) | 0.18 | 3 (2–4) | 6 (4–10) | 0.040* |
Values indicate the median (interquartile range).
DAS: disease activity score, US: ultrasound, Rem: remission, Non-rem: non-remission, CRP C-reactive protein, ESR erythrocyte sedimentation rate, MMP-3 matrix metalloproteinase, DAS disease activity score, CDAI clinical disease activity index, GS gray scale, PD power Doppler. P-values were estimated using Wilcoxon signed-rank test.
*P <0.05
**P <0.001
***P <0.0001.