Fig 3. Curcumin induces spermine catabolism through spermine oxidation in AGS cells.

AGS cells were treated for 48 hours and analyzed for SMOX (A) and SSAT (D) mRNA expression via qRT-PCR; (B-C) SMOX and SSAT protein levels by Western blot; and (E) SSAT enzyme activity. Graphs depict the mean values of at least 2 individual experiments, each measured in triplicate. Error bars = SEM; *p < 0.05. A representative western blot is presented in (C).