Table 1. Baseline characteristics of study patients by neurological status at hospital discharge.
| Variables | All patients (n = 796) |
Patients with favourable neurological outcome at hospital discharge (n = 94) |
Patients without favourable neurological outcome at hospital discharge (n = 702) |
p-value |
|---|---|---|---|---|
| Age (year), median (IQRa) | 66.8 (54.7–77.1) | 63.5 (50.0–73.8) | 67.2 (55.5–77.9) | 0.035 |
| Male, n (%) | 466 (58.5) | 70 (74.5) | 396 (56.4) | 0.001 |
| Neurological status 24 h before cardiac arrest, n (%) | 0.001 | |||
| CPCb 1 | 35 (4.4) | 6 (6.4) | 29 (4.1) | |
| CPC 2 | 312 (39.2) | 52 (55.3) | 260 (37.0) | |
| CPC 3 | 324 (40.7) | 31 (33.0) | 293 (41.7) | |
| CPC 4 | 125 (15.7) | 5 (5.3) | 120 (17.1) | |
| Comorbidities, n (%) | ||||
| Respiratory insufficiency | 579 (72.7) | 58 (61.7) | 521 (74.2) | 0.013 |
| Renal insufficiency | 357 (44.8) | 31 (33.0) | 326 (46.4) | 0.015 |
| Arrhythmia | 157 (19.7) | 22 (23.4) | 135 (19.2) | 0.335 |
| Diabetes mellitus | 287 (36.7) | 34 (36.2) | 253 (36.0) | 1 |
| Hypotension | 186 (23.4) | 18 (19.1) | 168 (23.9) | 0.363 |
| Heart failure, prior admission | 127 (16.0) | 22 (23.4) | 105 (15.0) | 0.050 |
| Heart failure, this admission | 164 (20.6) | 30 (31.9) | 134 (19.1) | 0.006 |
| Myocardial infarction, prior admission | 34 (4.3) | 9 (9.6) | 25 (3.6) | 0.013 |
| Myocardial infarction, this admission | 106 (13.3) | 26 (27.7) | 80 (11.4) | <0.001 |
| Metabolic or electrolyte abnormality | 139 (17.5) | 12 (12.8) | 127 (18.1) | 0.247 |
| Sepsis | 78 (9.8) | 4 (4.3) | 74 (10.5) | 0.062 |
| Pneumonia | 270 (33.9) | 21 (22.3) | 249 (35.5) | 0.011 |
| Metastatic or hematologic malignant disease | 163 (20.5) | 2 (2.1) | 161 (22.9) | <0.001 |
| Baseline depression in CNSc function | 231 (29.0) | 18 (19.1) | 213 (30.3) | 0.029 |
| Hepatic insufficiency | 153 (19.2) | 12 (12.8) | 141 (20.1) | 0.096 |
| Acute stroke | 41 (5.2) | 2 (2.1) | 39 (5.6) | 0.214 |
| Cardiopulmonary resuscitation during or before 2010, n (%) | 358 (45.0) | 31 (33.0) | 327 (46.6) | 0.015 |
a IQR, interquartile range.
b CPC, cerebral performance score
c CNS, central nervous system