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. 2018 Aug 23;13(8):e0202797. doi: 10.1371/journal.pone.0202797

Fig 2. Knockdown of Lp-PLA2 and YKL-40 in vivo.

Fig 2

(A) mRNA expression of Lp-PLA2 in the plaques of the vehicle, scrambled, Lp-PLA2 RNAi, YKL-40 RNAi, and combined Lp-PLA2 and YKL-40 RNAi groups (n = 12 /group); (B) mRNA expression of YKL-40 in the plaques from all groups (n = 12 /group); (C) The plasma concentrations of Lp-PLA2 in all groups (n = 24). (D) The plasma concentrations of YKL-40 in all groups (n = 24). Vehicle = vehicle group; scrambled = scrambled group (negative control). Lp-PLA2 RNAi = Lp-PLA2 RNAi group, YKL-40 RNAi = YKL-40 RNAi group, combined RNAi = combined Lp-PLA2 and YKL-40 RNAi group. Data are shown as the mean values ± S.D. *P<0.05 vs. vehicle groups; ▲P>0.05 vs. vehicle group.