Fig 6. In vivo protection by BDBV223 MPER mAb is mediated by Fc effects.

Groups of mice at five animals per group were injected with the indicated amounts of mAb by the intraperitoneal route at 24 hours after EBOV challenge. Kaplan-Meier survival curves, body weight and illness score curves are shown. *Survival difference between the rBDBV223-IgG1 and rBDBV223-IgG1-LALA recipients: 40 μg, p = 0.0158; 100 μg, p = 0.0494 (Mantel-Cox test).