Table 4a.

Associations of atrial fibrillation with all-cause and cause-specific mortality in the Cleveland Clinic CKD Registry

	Unadjusted HR (95% CI)	p- value	Adjusted* HR (95% CI)	p- value	Excluding those with malignancy Adjusted* HR (95% CI)
All-cause death	1.69 (1.62, 1.76)	<0.001	1.23 (1.18, 1.29)	<0.001	1.31 (1.25, 1.39)
	Unadjusted SHR (95% CI)		Adjusted* SHR (95% CI)		Adjusted* SHR (95% CI)
Cardiovascular mortality^	2.40 (2.26, 2.55)	<0.001	1.45 (1.36, 1.56)	<0.001	1.48 (1.37, 1.60)
Malignancy-related mortality^	0.80 (0.73, 0.89)	<0.001	0.87 (0.78, 0.97)	0.016	1.01 (0.86, 1.20)
Non-cardio non-malignancy mortality^	1.33 (1.23, 1.42)	<0.001	1.05 (0.96, 1.13)	0.28	1.02 (0.93, 1.12)

^*adjusted for age, sex, race, diabetes, hyperlipidemia, body mass index, albumin, hemoglobin, malignancy (except in analysis excluding patients with baseline malignancy), hypertension, coronary artery disease, congestive heart failure, cerebrovascular disease, peripheral vascular disease, insurance type, ACE/ARB, beta blocker use, statins use, smoking, and eGFR

Hazard and sub-hazard ratios (HR and SHR) presented in adjusted models were pooled using MIanalyze from 5 multiply imputed datasets;

^{^}N = 62,219 due to some missing cause of death.