Table 4b.
Unadjusted HR (95% CI) |
p- value |
Adjusted* HR (95% CI) |
p- value |
|
---|---|---|---|---|
All-cause death | 1.67 (1.57, 1.78) | <0.001 | 1.24 (1.16, 1.32) | <0.001 |
SHR (95% CI) | SHR (95% CI) | |||
Cardiovascular mortality^ | 2.26 (2.06, 2.47) | <0.001 | 1.45 (1.31, 1.61) | <0.001 |
Malignancy-related mortality^ | 0.91 (0.79, 1.04) | 0.17 | 0.91 (0.78, 1.07) | 0.24 |
Non-cardio non-malignancy mortality^ |
1.33 (1.19, 1.47) | <0.001 | 1.08 (0.96, 1.21) | 0.21 |
Cardiovascular sub-categories | ||||
Ischemic heart disease^ | 2.03 (1.78, 2.32) | <0.001 | 1.28 (1.10, 1.48) | 0.001 |
Heart failure^ | 2.63 (1.94, 3.56) | <0.001 | 1.22 (0.86, 1.73) | 0.22 |
Cerebrovascular disease^ | 1.73 (1.30, 2.29) | <0.001 | 1.30 (0.95, 1.78) | 0.10 |
Other cardiovascular diseases^ | 2.35 (2.00, 2.76) | <0.001 | 1.69 (1.40, 2.03) | <0.001 |
adjusted for age, sex, race, diabetes, hyperlipidemia, body mass index, albumin, hemoglobin, malignancy (except in analysis excluding patients with baseline malignancy), hypertension, coronary artery disease, congestive heart failure, cerebrovascular disease, peripheral vascular disease, insurance type, ACE/ARB, beta blocker use, statins use, smoking, eGFR and proteinuria
Hazard and sub-hazard ratios presented in adjusted models were pooled using MIanalyze from 5 multiply imputed datasets;
N = 30,033 due to some missing cause of death.