. Author manuscript; available in PMC: 2019 Jun 1.

Published in final edited form as: J Drug Target. 2017 Dec 27;26(5-6):448–457. doi: 10.1080/1061186X.2017.1419355

Table 1.

Physicochemical characterizations of DOX-loaded POEG-b-PSAHA micelles.

Micelles	Mass ratio (mg: mg)^a	Size (nm)^b	PDI^C	DLC(%)^d	DLE(%)^e	Stability^f
POEG-b-PSAHA:		63.7 ± 0.7	0.14 ± 0.01
POEG-b-PSAHA:	5:1	78.4 ± 0.4	0.22 ± 0.01	14.9	89.3	5 d
DOX
POEG-b-PSAHA:	10: 1	75.9 ± 0.6	0.18 ± 0.01	8.2	90.6	9 d
DOX
POEG-b-PSAHA:	20:1	73.9 ± 0.9	0.26 ± 0.01	4.5	93.5	17 d
DOX
POEG-b-PSAHA:	30: 1	79.7 ± 0.3	0.23 ± 0.01		92.3	32 d
DOX				3.0
POEG-b-PSAHA:	50:1	86.6 ± 0.2	0.20± 0.01	1.9	96.7	50 d
DOX

^a)

DOX concentration in micelles was kept at 0.5 mg/mL.

^b)

Measured by dynamic light scattering particle sizer.

^c)

PDI = polydispersity index.

^d)

DLC = drug loading capacity.

^e)

DLE = drug loading efficiency.

^f)

Data mean there was no noticeable size change and visible precipitates during the follow-up period at 4 °C.